5AM Venture Management, LLC
Holdings as of 2026-06-30, filed 2026-08-14
This is history, not a current position. These holdings describe 2026-06-30, and the report became public 45 days later. The portfolio has changed since.
Aggregates
computed from the positions belowPositions reported
16
Value reported by manager
$287.9M
Sum of our stored positions
$287.9M
should match the line above
Disclosure lag
45 d
quarter end to filing
Top 5 concentration
52.1%
of the positions shown
New positions
0
vs previous quarter
Exited
0
vs previous quarter
Option positions
0
puts and calls
Positions
16 largest shown| Issuer | Class | Value | Shares | Type | CUSIP |
|---|---|---|---|---|---|
| MAPLIGHT THERAPEUTICS INC | COM | $34M | 950,011 | — | 56565P103 |
| TYRA BIOSCIENCES INC | COM | $32.9M | 1,029,298 | — | 90240B106 |
| ENTRADA THERAPEUTICS INC | COM | $29.9M | 4,056,379 | — | 29384C108 |
| PHARVARIS N V | COM | $27.6M | 797,600 | — | N69605108 |
| CAMP4 THERAPEUTICS CORP | COM | $25.6M | 5,869,091 | — | 13463J101 |
| ARTIVA BIOTHERAPEUTICS INC | COM | $22.8M | 2,353,304 | — | 04317A107 |
| TECTONIC THERAPEUTIC INC | COM | $20.9M | 606,660 | — | 878972108 |
| ZENTALIS PHARMACEUTICALS INC | COM | $19.1M | 3,947,913 | — | 98943L107 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | $18.5M | 497,270 | — | 15117B202 |
| EYEPOINT INC | COM NEW | $15M | 1,050,000 | — | 30233G209 |
| BIOHAVEN LTD | COM | $11M | 738,972 | — | G1110E107 |
| SURROZEN INC | COM NEW | $7M | 271,250 | — | 86889P208 |
| SKYE BIOSCIENCE INC | COM NEW | $6.7M | 9,681,763 | — | 83086J200 |
| ALX ONCOLOGY HLDGS INC | COM | $6.3M | 3,057,325 | — | 00166B105 |
| PROTARA THERAPEUTICS INC | COM STK | $5.2M | 1,369,782 | — | 74365U107 |
| SILENCE THERAPEUTICS PLC | ADS | $5.2M | 476,200 | — | 82686Q101 |
Values are shown exactly as filed. Before 2023 managers reported in thousands of dollars and afterwards in whole dollars; the reporting unit is not always determinable from the document, so nothing is converted automatically.
Source: U.S. Securities and Exchange Commission, Form 13F · as of 2026-08-14